研究组成员

张孟贤

博士后

  • 邮箱:sandy_zhang@ncu.edu.cn

  • 地址:

  • 研究方向:

个人简介

教育经历:

(1) 2013-09 2017-06, 南开大学, 生物学, 学士

(2) 2017-09 2024-06, 清华大学, 生物学, 博士

2023年获得清华大学综合二等奖学金,2024年获得南昌大学A类博士后奖学金,2024年获得南昌大学基础医学院院内基金资助。


研究方向

基于CRISPR系统的胃壁细胞分化调控因子筛选及机制探究、肠道上皮细胞在损伤修复中的作用与机制探究、利用类器官炎症损伤修复模型筛选促进肠道再生的肠道菌群代谢物。


近五年代表性论文

(1)Zhang, M., Liu, Y., & Chen, Y. G. (2020). Generation of 3D human gastrointestinal organoids: principle and applications. Cell Regeneration, 9(1), 6.

(2)Yu, S., Zhang, M., Ye, Z., Wang, Y., Wang, X., & Chen, Y. G. (2023). Development of a 32-gene signature using machine learning for accurate prediction of inflammatory bowel disease. Cell Regeneration, 12(1), 8.

(3)Li, H., Wang, Y., Zhang, M., Wang, H., Cui, A., Zhao, J., ... & Chen, Y. G. (2021). Establishment of porcine and monkey colonic organoids for drug toxicity study. Cell Regeneration, 10, 1-10.

(4)Li, H., Wang, X., Wang, Y., Zhang, M., Hong, F., Wang, H., ... & Chen, Y. G. (2022). Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium. Cell Regeneration, 11(1), 19.

(5)Zhang, F., Wu, P., Wang, Y., Zhang, M., Wang, X., Wang, T., ... & Wei, D. (2020). Identification of significant genes with prognostic influence in clear cell renal cell carcinoma via bioinformatics analysis. Translational andrology and urology, 9(2), 452.

(6)Wei, S., Li, M., Song, W., Liu, J., Yu, S., Wang, Y., Zhang, M., ... & Chen, Y. G. (2023). The cyclooxygenase-expressing mesenchyme resists intestinal epithelial injury by paracrine signaling. Cell Regeneration, 12(1), 30.