个人简介

南昌大学生物医学创新研究院PI。中央引导地方专项-国家优青培育人才，省级人才。 多年来从事生殖生物学和生殖医学研究，构建了一流的精子离子通道和蛋白质翻译后修饰研究平台。目前主持10余项国家级和省部级课题，担任国家、教育部及多个省份的专家库专家，多个协会专委会委员和理事以及多个学术期刊的副主编和审稿人。获江西省自然科学奖以及江西省医学科技奖。在J Hazard Mater、Hum Reprod等杂志发表论文56篇（H-index：19）。

研究方向

1）研究蛋白质翻译后修饰（特别是新型赖氨酸翻译后修饰）在调控精子运动和卵巢衰老中的作用机制，及这些修饰异常与弱精子症、卵巢生理性衰老以及卵巢早衰和卵巢功能低下等生理和病理中的作用机制。

2）研究环境污染物（内分泌干扰物、重金属以及微纳米塑料）的生殖毒理、干预及其与男和女性生殖健康的相关性。

3）利用睾丸和卵巢类器官进行生殖毒性和药理学研究，构建不育的精准诊疗体系。

代表性论文

1. Wenqing Xu, Yangyang Yuan, Yan Tian, Cheng Cheng, Ying Chen, Lianjie Zeng, Yuan Yuan, Dandan Li, Liping Zheng, Tao Luo*. Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice. Journal of Hazardous Materials, 2023, 454: 131470.

2. Lianjie Zeng#, Chong Zhou#, Wenqing Xu, Yupei Huang, Wencan Wang, Zhangqiang Ma, Jian Huang, Jia Li, Liaoliao Hu, Yue Xue, Tao Luo*, Zheng Liping*. The ovarian-related effects of polystyrene nanoplastics on human ovarian granulosa cells and female mice. Ecotoxicology and Environmental Safety, 2023, 257: 114941.

3. Yuan Yuan, Yiwen Qin, Meng Wang, Wenqing Xu, Ying Chen, Liping Zheng, Wen Chen*, Tao Luo*. Microplastics from agricultural plastic mulch films: A mini-review of their impacts on the animal reproductive system. Ecotoxicology and Environmental Safety, 2022, 244: 114030.

4. Houyang Chen, Liang Tang, Qing Hong, Tingting Pan, Shiqi Weng, Jie Sun, gene 1 (TDRG1) encodes a progressive motility-associated protein in human spermatozoa. Human Reproduction, 2021, 36(2): 283–292.

5. Yi-min Cheng#, Zhen Peng#, Hou-yang Chen, Ting-ting Pan, Xiao-nian Hu, Fang Wang, Tao Luo*. Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility. Human Reproduction, 2020, 35(3): 494-503.

6. Fang Wang, Houyang Chen, Ying Chen, Yimin Cheng, Jia Li, Liping Zheng, Xuhui Zeng, Tao Luo*. Diet-induced obesity is associated with altered expression of sperm motility-related genes and testicular post-translational modifications in a mouse model. Theriogenology, 2020, 158: 233-238.

7. Yi-min Cheng, Xiao-nian Hu, Zhen Peng, Ting-ting Pan, Fang Wang, Hou-yang Chen, Wen-qiong Chen, Yu Zhang, Xu-hui Zeng*, Tao Luo*. Lysine glutarylation in human sperm is associated with progressive motility. Human Reproduction, 2019, 34(7): 1186-1194.

8. Tao Luo, Hou-yang Chen, Qian-xing Zou, Tao Wang, Yi-min Cheng, Hua-feng Wang, Fang Wang, Zhong-lin Jin, Ying Chen, Shi-qi Weng, Xu-hui Zeng*. A novel copy number variation in CATSPER2 causes idiopathic male infertility with normal semen parameters. Human Reproduction, 2019, 34(3): 414-423.