NOW: HOME - FACULTY - Research Groups - GAO Ping Lab
E-mail：pgao2@ustc.edu.cn
Address：Room 429, Medical Science and Technology Innovation Center
Educational Experience
1989-1992, Master's Student, Chinese People's Liberation Army Military Medical Academy (301 Hospital)
1999-2003, Ph.D. Student, Osaka University, Japan
2003-2005, Postdoctoral Fellow, Immunology Branch, National Cancer Institute (NCI/NIH), USA
2005-2007, Postdoctoral Fellow, Johns Hopkins University School of Medicine
Work Experience
2007-2010, Research Associate, Johns Hopkins University School of Medicine
2010-2017, Professor, School of Life Sciences, University of Science and Technology of China
2017-2022, Professor, School of Medicine, South China University of Technology
2022-2025, Professor, Southern Medical University / Guangdong Provincial People's Hospital
2025-Present, Professor, School of Basic Medical Sciences, Nanchang University / The First Affiliated Hospital of Nanchang University
Academic Part-time Positions
Director of the China Anti-Cancer Association
Member of the Cell Metabolism Branch, Chinese Society for Cell Biology
Award Information
2005 Fellow Award for Research Excellence, National Institutes of Health
2008 Young Investigator Award, Johns Hopkins University School of Medicine
2013 Distinguished Professor (“Anhui 100 Talents” Program)
2016 First Prize, K. C. Wang Teaching Excellence Award; Distinguished Professor, Chinese Academy of Sciences
2017 Outstanding Mentor Award, Chinese Academy of Sciences
2019 Leading Talent in Science and Technology Innovation, Pearl River Talent Plan (Guangdong)
The research focuses on tumor metabolism and tumor immunology. It investigates the mechanisms by which metabolic alterations in tumors contribute to tumorigenesis and progression, including the impact of these alterations on tumor cell fate, the remodeling of the tumor microenvironment, and the regulation of tumor immunity. The work aims to elucidate novel mechanisms of tumor pathogenesis, identify new therapeutic targets, and provide novel strategies and insights for clinical cancer treatment.
1. Wei H, Suo C, Gu X, et al., Sun L*, Zhang H*, and Gao P*. AKR1D1 suppresses liver cancer progression by promotingbile acid metabolism-mediated NK cell cytotoxicity. Cell Metabolism. 2025.
2. Hao Y, Zhou Z, Liu R, Shen S, Liu H, Zhou Y, Sun Y, Mao Q, Zhang T, Li S, Liu Z, Sun L*, Gao P*, Zhang H*. Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance. Nat Chem Biol. 2025.
3. Yan R, Zhang P, et al., Zhang H*, Gao P*. Carnosine Regulation of Intracellular pH Homeostasis Promotes Lysosome-dependent Tumor Immunoevasion. Nature Immunology. 2024.
4. Zhu C, Yan K, et al., Gao P*, Lian Z*. Targeting OXCT1-mediated ketone metabolism reprograms macrophages to promote antitumor immunity via CD8+ T cells in hepatocellular carcinoma. Journal of Hepatology. 2024.
5. Ma W, Sun Y, et al., Gao P* and Zhang H*. OXCT1 functions as a succinyltransferase to promote hepatocellular carcinoma via succinylating LACTB. Molecular Cell. 2024
6. Sun L, Suo C, Zhang T, Shen S, et al., Zhang H*, Gao P*. ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism. Nat Chem Biol. 2023.
7. Zhang T, Sun L, et al., Gao P*, Zhang H*. ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein1. Nat Cancer. 2022.
8. Li S, Huang D, et al., Duan X*, Zhang H*, Gao P*. Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis. Nature Metabolism. 2020.
9. Zhong X, et al., Zhang H*, Zhou Q* and Gao P*. Mitochondrial dynamics is critical for the full pluripotency and embryonic developmental potential of pluripotent stem cells. Cell Metabolism. 2019.
10. Gao P*, et al., Dang CV*.c-myc suppression of mir-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature. 2009.
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