NOW: HOME - FACULTY - Research Groups - TAO Jinsong Lab
E-mail：tjs9181@163.com
Address：Room 335, Medical Science and Technology Innovation Center
Education
2017.08-2021.10, Ph.D., Institute of Chinese Medical Sciences, University of Macau
2013.09-2016.06, M.S., School of Pharmacy, Nanchang University
2013.09-2016.06, Joint M.S. Training, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2009.09-2013.06, B.S., School of Pharmacy, Nanchang University
Professional Experience
2026.07-Present, Distinguished Research Fellow, Institute of Biomedical Innovation / College of Pharmacy, Nanchang University
2022.07-2026.06, Postdoctoral Fellow, College of Pharmacy, University of Michigan, Ann Arbor
2022.01-2022.06, Postdoctoral Fellow, Institute of Applied Physics and Materials Engineering, University of Macau
2016.10-2017.07, Researcher, Antibody Process Research Institute, Shanghai Hengrui Pharmaceutical Co., Ltd.
We focuses on immune dysregulation and precision intervention in major diseases, developing immunomodulatory therapeutics and delivery technologies, include myeloid immune regulation, antigen presentation remodeling, precision immune delivery, and translational evaluation of immunotherapeutics, with the goal of advancing new therapeutic strategies for cancer, inflammation, and immune-related diseases.
1. Myeloid immune regulation: remodeling the functions of neutrophils, macrophages, and dendritic cells to enhance antitumor immune responses.
2. Tumor antigen presentation remodeling: improving tumor antigen processing, MHC I presentation, and T-cell immune recognition.
3. Precision immune drug delivery: constructing nanomedicine, mRNA-LNP, and membrane-vesicle platforms for targeted delivery of immunotherapeutics.
4. Translational evaluation of immunotherapeutics: establishing efficacy, safety, and in vivo fate evaluation systems to promote translational applications.
1. Jinsong Tao#, Hongyi Zhao#, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Wei Gao*, Duxin Sun*. Albumin-Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8⁺ T Cell Immunity. Advanced Science, 2026, 13(29): e23603.
2. Hong-Yi Zhao#, Jinsong Tao#, Luchen Zhang, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Hannah Myatt, Duxin Sun*. Design of an Oral STING Agonist through Intramolecular Hydrogen Bond Ring Mimicking to Achieve Complete Tumor Regression. Journal of Medicinal Chemistry, 2025, 68(11): 11365-11385.
3. Yaxin Cheng#, Jinsong Tao#, Yaqi Zhang#, Long Xi, Run Han, Meng Xu, Simon Ming-Yuen Lee, Wei Ge, Yong Gan*, Ying Zheng*. Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence. Molecular Pharmaceutics, 2023, 20(6): 3187-3201.
4. Jinsong Tao, Zhengjie Wei, Yaxin Cheng, Meng Xu, Qiuxia Li, Simon Ming-Yuen Lee, Wei Ge, Kathy Qian Luo, Xueqing Wang, Ying Zheng*. Apoptosis-Sensing Xenograft Zebrafish Tumor Model for Anticancer Evaluation of Redox-Responsive Cross-linked Pluronic Micelles. ACS Applied Materials & Interfaces, 2022, 14(35): 39775-39786.
5. Jinsong Tao#, Zhengjie Wei#, Meng Xu, Long Xi, Yaxin Cheng, Simon Ming-Yuen Lee, Wei Ge, Ying Zheng*. Particle Integrity and Size Effect on the Journey of Polymeric Nanocarriers in Zebrafish Model and the Correlation with Mice. Small, 2021, 17: 2103584.
6. Jinsong Tao, Zhengjie Wei, Yuan He, Xingyang Yan, Simon Ming-Yuen Lee, Xueqing Wang, Wei Ge, Ying Zheng*. Toward understanding the prolonged circulation and elimination mechanism of crosslinked polymeric micelles in zebrafish model. Biomaterials, 2020, 256: 120180.
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Tel：+86-0791-83968485
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