NOW: HOME - FACULTY - Research Groups - Wu Xia Lab
E-mail：wuxia@ncu.edu.cn
Address：Room 366, Medical Science and Technology Innovation Center
Education
2006-2010, East China Normal University, B.Sc., Biological Sciences
2010-2013, East China Normal University, M.Sc., Optics（Biophysics）
2013-2016, École Normale Supérieure, Paris, Ph.D., Biology
Professional Experience
2016.10-2018.05, École Normale Supérieure, Paris, Postdoctoral Researcher
2018.06-2019.05, Curie Institute, France, Postdoctoral Researcher
2019.06-2024.04, Sun Yat-sen University, Zhongshan School of Medicine, Distinguished Researcher (Special-term)
2024.05-2026.05, Sun Yat-sen University, Zhongshan School of Medicine; Associate Professor
2026.06-Present, Institute of Biomedical Innovation, Nanchang University, Research professor
Academic Appointments
None
Honors and Awards
Distinguished Young Scholar, Guangdong Natural Science Foundation
Tumor Immunology and Epigenetic Regulation:
We develop and apply cutting-edge single-cell and multi-omics technologies to investigate the composition, functional states, and dynamic regulation of immune cells within the tumor microenvironment. Our research aims to identify novel immune cell populations and immunoregulatory targets associated with responses to cancer immunotherapy, while elucidating the epigenetic mechanisms that govern tumor initiation, progression, and therapeutic outcomes.
1. Qizhao Huang#, Xia Wu#, Zhiming Wang#, Xiangyu Chen#, Lisha Wang, Yijun Lu, Dan Xiong, Qiao Liu, Yuhan Tian, Huayu Lin, Junyi Guo, Shuqiong Wen, Wei Dong, Xiaofan Yang, Yuchen Yuan, Zhengliang Yue, Shun Lei, Qing Wu, Ling Ran, Luoyingzi Xie, Yifei Wang, Leiqiong Gao, Qin Tian, Xinyuan Zhou, Beicheng Sun*, Lifan Xu*, Zhonghui Tang*, Lilin Ye*. The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes. Cell, 2022, 185(22): 4049-4066.
2. Xia Wu#, Dan Xiong#, Rong Liu#, Xingqiang Lai#, Yuhan Tian#, Ziying Xie, Li Chen, Lanqi Hu, Jingjing Duan, Xinyu Gao, Xian Zeng, Wei Dong, Ting Xu, Fang Fu, Xin Yang, Xinlai Cheng, Dariusz Plewczynski, Minji Kim, Wenjun Xin, Tianyun Wang, Andy Peng Xiang, Zhonghui Tang*. Evolutionary divergence in CTCF-mediated chromatin topology drives transcriptional innovation in humans. Nature Communications, 2025, 16: 2941.
3. Xia Wu#, Yaqun Liu#, Yves d’Aubenton-Carafa, Claude Thermes, Olivier Hyrien*, Chun-Long Chen*, Nataliya Petryk*. Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing. Nature Protocols, 2023, 18(4): 1260-1295.
4. Yaqun Liu, Xia Wu, Yves d’Aubenton-Carafa, Claude Thermes, Chun-Long Chen. OKseqHMM: a genome-wide replication fork directionality analysis toolkit. Nucleic Acids Research, 2023, 51(4): e22.
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校外链接
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Tel：+86-0791-83968485
E-mail：ibi@ncu.edu.cn
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