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马朝林课题组

马朝林

研究员、博导

基础信息

chaolinma@ncu.edu.cn

个人简介

教育经历

2004.07-2006.03 美国亚利桑那州立大学,生物医学工程,博士后

2001.09-2004.06 复旦大学,神经生物学专业,博士研究生

1998.07-2001.06 山东师范大学,动物学专业,硕士研究生

1985.09-1988.06 湖南农学院衡阳分院,生物学专业,大学

工作经历

2013.07- 至今 南昌大学生命科学研究院,研究员

2011.09-2013.06 美国达特茅斯学院,Research Scientist

2006.04-2011.08 美国亚利桑那州立大学,Research Scientist

研究方向

长期从事认知神经生物学科研工作,擅长运用行为电生理学和行为药理学方法研究前额叶皮层认知功能。在工作记忆、行为抑制和行为抉择等认知功能的研究中取得一定的成绩。曾研究猴前额叶皮层去甲肾上腺素2受体在行为抑制功能中的作用机制,为2受体激动剂应用于临床治疗儿童注意力缺损多动症(ADHD)提供了实验依据。在国外工作9年期间,主要应用电生理方法解码大脑皮层神经元对运动的编码。2013年回国后,继续深入研究前额叶神经元对工作记忆与行为抉择等认知功能的编码。至今为止,作为通讯作者或第一作者,在国际期刊如《Biological Psychiatry》、《Frontiers in Neuroscience》和《Neuroscience Bulletin》等上发表了30多篇研究论文。

代表性论文

1) Yiting Li#, Wenqu Yin#, Jiawen Li, Shanglin Zhou, Chaolin Ma*, Peng Yuan*, Baoming Li*. Stable sequential dynamics in prefrontal cortex represents subjective estimation of time. elife, 2024. doi:10.1101/2024.02.26.582.

2) Xiaona Wang#, Qian Wang, Min Song, Yihui Wang, Xianzhi Shen, Yanyun Sun, Chun Guo, Panpan Geng, Chaolin Ma*, Xinchun Jin*. Chronic but not acute nicotine treatment ameliorates acute inflammation-induced working memory impairment by increasing CRTC1 and HCN2 in adult male mice. CNS Neurosci Ther, 2024, 30(2): e14627.

3) Yinging Han#, Qianyu Dong#, Jiyun Peng, Baoming Li, Cong Sun*, Chaolin Ma*. Laminar Distribution of Cannabinoid Receptor 1 in the Prefrontal Cortex of Nonhuman Primates. Mol Neurobiol, 2023. doi: 10.1007/s12035-023-03828-4.

4) Yanping Wang#, Weihong Du, Yanyun Sun, Junfang Zhang, Chaolin Ma*, Xinchun Jin*. CRTC1 is a potential target to delay aging-induced cognitive by

deficit by protecting the integrity of the blood-brain barrier via inhibiting inflammation. J Cereb Blood Flow Metab, 2023, 43(7): 1042-1059.

5) Weiming Sun#, Xiangli Dong, Guohua Yu, Yang Yang, Binjun He, Yingming Wei, Shijin Li, Zhen Feng, Chaolin Ma*. Behavioral assessment scale of consciousness for nonhuman primates: A Delphi study. Sci Prog, 2023, 106(3): 368504231200995.

6) Mingzhe Yang, Qiangpei Fu, Xu Hu, Baoming Li, Chaolin Ma*. Behavior of Rats in a Self-Paced Risky Decision-Making Task Based on Definite Probability. Brain Sci, 2022, 12(6): 795.

7) Weiming Sun#, Guanxiu Liu, Changhao Le, Can Li, Xiangli Dong, Chaolin Ma*. The Evaluation Indexes Suitable for Nonhuman Primates can be Extracted from Clinical Consciousness Disorder Assessment Scales: A Hypothesis. J Integr Neurosci, 2022, 21(6): 159.

8) Yan Ma#, Weiming Sun, Nanrun Zhou, Jiping He, Chaolin Ma*. Neurons in Primary Motor Cortex Encode External Perturbations during an Orientation Reaching Task. Brain Sci, 2021, 11(9): 1125.

9) Jie Luo#, Hongfei Zhang, Jiachen Lu, Chaolin Ma*, Tingtao Chen*. Antidiabetic effect of an engineered bacterium Lactobacillus plantarum-pMG36e-GLP-1 in monkey model. Synth Syst Biotechnol, 2021, 6(4): 272-282.

10) Weiming Sun#, Chaolin Ma*, Jiang Xu, Jiping He. Reduction in post-spinal cord injury spasticity by combination of peripheral nerve grafting and acidic fibroblast growth factor infusion in monkeys. J Int Med Res, 2021, 49(6): 3000605211022294.