个人简介

魏劲松，博士，特聘研究员，博士生导师。2015年本硕连读毕业于西北农林科技大学，2021年博士毕业于复旦大学，2021-2023年在复旦大学进行博士后训练，2023-2025年任同济大学附属第十人民医院助理研究员。2025年5月以高层次人才-特聘研究员入职南昌大学。研究方向为肝脏细胞命运调控。近五年以第一作者身份（含共同）于国际权威期刊Nature Chemical Biology、Journal of Biological Chemistry、Genome Biology、Advanced Science和Chemical Engineering Journal等发表系列性研究论文。主持国家自然科学基金青年科学基金。

研究方向

构建人源类器官及小鼠创新疾病模型，开发药物治疗新靶点、新策略，并经体内外联合研究深入阐述病理机制。尤其关注肝脏疾病造模与机制研究。

代表性论文

1. Wei, J. #, Cao, Z. #, Li, Q., Li, X., Wang, Q., Zhang, Y., Zhang, R., Wu, X., Dai, Q., Li, X., Sun, F., Zhou, Z., Jiao, S. and Zhao, B. (2025) Nuclear ubiquitination permits Hippo-YAP signal for liver development and tumorigenesis. Nature Chemical Biology, accepted.

2. Wei, J. #, Ran, G. #, Wang, X., Jiang, N., Liang, J., Lin, X., Ling, C., and Zhao, B. (2019) Gene manipulation in liver ductal organoids by optimized recombinant adeno-associated virus vectors. Journal of Biological Chemistry, 294, 14096-14104.

3. Liang J. #, Wei J. #(co-first), Cao J#., Qian J., Gao R., Li X., Wang D., Gu Y., Dong L, Yu J., Zhao B., Wang X. (2023) In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation. Genome Biology, 24, 251

4. Liu, G.#, Wei, J.#(co-first), Li, X., Tian, M., Wang, Z., Shen, C., Sun, W., Li, C., Li, X., Lv, E., Tian, S., Wang, J., Xu, S., and Zhao, B. (2022) Near-Infrared-Responded High Sensitivity Nanoprobe for Steady and Visualized Detection of Albumin in Hepatic Organoids and Mouse Liver. Advanced Science, 9, e2202505

5. Tian, M. #, Wei, J. #(co-first), Lv, E. #, Li, C., Liu, G., Wang, Q., Shen, C., Man, B., Wang, J., Zhao, B. and Xu, S. (2024) Drug evaluation platform based on non-destructive and real-time in situ organoid fate state monitoring by graphene field-effect transistor. Chemical Engineering Journal, 498, 155355

6. Wei, J., Zhang, W., and Zhao, B. (2023) Human liver organoid: modeling liver steatosis and beyond. Cell Regeneration, 12, 17