
NOW: HOME - FACULTY - Research Groups - Yang Lin Lab
E-mail:lin.yang@ncu.edu.cn
Address:Room 252, Medical Science and Technology Innovation Center, Nanchang University
Education:
2008.09 - 2012.07: School of Life Sciences and Food Engineering, Nanchang University,Bachelor
2012.09 - 2015.07: School of Life Sciences and Food Engineering, Nanchang University,Master
2015.10 - 2020.11: School of Medicine, Technical University of Munich, Germany, PhD
Professional Experience:
2020.11 – 2025.12: Institute of Lung Health and Immunology (LHI), Schmid Lab, and Research units of Precision Regenerative Medicine (PRM), Schiller Lab, Helmholtz Munich, Postdoctoral Fellow
2024.04-2025.11: DZL Academy Training Program "Careers in Respiratory Medicine"
2026.1- Present: Institute of Biomedical Innovation, School of Pharmacy, and The First Affiliated Hospital, Nanchang University, Junior Principal Investigator (PI)
Academic Appointments:
German Center for Lung Research (DZL), Academic Member
American Thoracic Society (ATS), Academic Member
German Respiratory Society (DGP), Member
Co-organized the DPLD Young Investigator Symposium, Heidelberg, Germany, 2023
Served as a reviewer for more than 20 multidisciplinary high-impact peer-reviewed journals, including Signal Transduction and Targeted Therapy, Star Protocols, Particle and Fibre Toxicology, Frontiers in Immunology, Small, etc.
Awards and Honors:
2025.07 Shared Second Prize, Scientific Publication Award 2025, German Center for Lung Research (DZL) Association, Heidelberg, Germany
2025.04 Best Experimental Medicine Paper Award 2025 by German Respiratory Society (DGP), Leipzig, Germany (Relevant news link: Pressemitteilung)
2025.02 Shared Best Oral Presentation Award, CRSingapore2025 - Connecting Continents in Delivery Science Conference, Singapore
2024.06 Best Poster Award, Imaging Group, Annual Conference of German Center for Lung Research (DZL), Bad Nauheim, Germany
2023.06 Best Scientific Image Award, Scientific Image Competition Hosted by Helmholtz Imaging (Germany-wide), Hamburg, Germany (The scientific image "Lung Health and Immunity" won the first place in the professional jury group, Relevant news link: Best Scientific Image 2023: Who won this year’s contest? – helmholtz-imaging.de
The Intelligent Respiratory and Inhalation Medicine Lab (IRIM Lab) is dedicated to advancing precision respiratory medicine by integrating multiscale imaging, single-cell and spatial omics, artificial intelligence, human organotypic models, and inhalation bioengineering. Our mission is to define actionable mechanisms of lung disease and translate them into targeted, patient-tailored inhalation therapies for infectious and chronic respiratory disorders.
The lab builds on my training in the Schmid Lab, focused on precision inhalation aerosol delivery and AI computer vision-enabled quantitative lung imaging, and in the Schiller Lab, centered on lung infection, inflammation, fibrosis, and regeneration using single-cell/spatial omics and human organotypic systems. Together, these complementary experiences shaped the foundation of IRIM Lab’s research framework and its goal of linking disease mechanisms to therapeutic innovation.
Our long-term vision is to create a next-generation framework for personalized inhalation medicine that integrates mechanistic disease understanding with technological innovation, including the LungVis Family, and precision therapeutic design. By bridging fundamental discovery and clinical translation, IRIM Lab seeks to deliver more precise, effective, and clinically relevant therapies for lung disease.
1.Yang L*, Han L*, Schmid O, Chen C*. Precision dosimetry in pulmonary drug delivery,Nature Reviews Bioengineering, 2025, https://doi.org/10.1038/s44222-025-00356-9
2.Liu Q, Yang L, Li C, Han L, Wilmot J, … & Rehberg M, Alveolar macrophages initiate the spatially targeted recruitment of neutrophils after nanoparticle inhalation, Sciences Advances, 2025, 11 (45):edax8586
3.Yang L*, Liu Q, Kumar P, Sengupta, A…., Schmid O*. LungVis 1.0: an automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages, Nature Communications, 2024, 10138 (15).https://doi.org/10.1038/s41467-024-54267-1
Helmholtz press release LungVis 1.0: Precision Therapy for Lung Diseases with AI-Driven Imaging
4.Zhou Q+, Liu Q+, Wang Y, Chen, J*, Schmid O, Rehberg M, Yang L*, Bridging smart nanobiotechnology with clinically relevant models and advanced imaging for precision drug delivery,Advanced Science, 2024, 2308659, https://doi.org/10.1002/advs.202308659
5.Lang, NJ, Gote-Schniering J, Gonzalez. DP, Yang L,...& Schiller H. Ex vivo tissue perturbations coupled to single cell RNA-seq reveal multi-lineage cell circuit dynamics in human lung fibrogenesis.Science Translational Medicine, 2023, 15(725), DOI:10.1126/scitranslmed.adh0908