FACULTY

FACULTY

XU Hong Lab

NOW: HOME - FACULTY - Research Groups - XU Hong Lab

XU Hong

Research Fellow Ph.D. Supervisor

  • E-mail：xuhong@ncu.edu.cn

  • Address：Room 211, Medical Science and Technology Innovation Center

Biography
Research
Group Members
Publications

Education

1992.09–1996.07 Shandong Normal University, Biology, B.S.

1996.09–1999.07 China Pharmaceutical University, Molecular Pharmacology, M.S.

1999.09–2003.12 Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Biochemistry & Molecular Biology, Ph.D.

Professional Experience

2004.07–2010.12 Postdoctoral Fellow, Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania (UPenn), USA

2011.01–2012.11 Distinguished Professor, Doctoral Supervisor, Institute of Life Sciences, Nanchang University

2012.12–2023.10 Professor, Doctoral Supervisor, Institute of Life Sciences, Nanchang University

2023.11–present Professor, Doctoral Supervisor, Institute of Biomedical Innovation, Nanchang University

Academic Appointments

Council Member, Zebrafish Branch of the China Zoological Society

Deputy Director, Autism Professional Committee of Jiangxi Psychological Society

Council Member, Jiangxi Society for Neuroscience

Council Member, Jiangxi Society for Cell Biology

Awards and Honors

2023 Second Prize of Jiangxi Provincial Natural Science Award (Ranked 1st), Models and Interventions for Rare Neurodevelopmental Disorders



Neural Circuit Development and Disease，Currently focused on neurodevelopmental psychiatric disorders such as autism, this research aims to elucidate their pathogenic mechanisms at the molecular, cellular, and neural circuit levels, providing experimental evidence for the diagnosis, prevention, and treatment of neurodevelopmental disorders.



  1. Zhu J, Wang H, Chen YR, Yan LY, Han YY, Liu LY, Cao Y, Liu ZZ, Xu HA*. The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish. Neurosci Bull. 2020 Sep;36(9):1023-1034.

  2. Long X, Wang S, Luo Z, Zhang, X, Xu HA* . Comparison of three administration modes of establishing a zebrafish seizure model induced by NMDA. World Journal of Psychiatry. 2020 July 19; 10(7): 150-161.

  3. Ying Chen, Hantsing Wang, Fang Wang, Chen Chen, Peng Zhang, Dandan Song, Tao Luo, Hong Xu*, Xuhui Zeng*. Sperm motility modulated by Trpv1 regulates zebrafish fertilization. Theriogenology. 2020 Jul 15;151:41-51.

  4. Liu ZZ, Guo J, Lu Y, Liu W, Fu X, Yao T, Zhou Y, Xu HA*. Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome. Int J Exp Pathol. 2019 Aug;100(4):234-243.

  5. Luo ZW, Wang HT, Wang N, Sheng WW, Jin M, Lu Y, Bai YJ, Zou SQ, Pang YL, Xu HA*, Zhang X* . Establishment of an adult zebrafish model of retinal neurodegeneration induced by NMDA. Int J Ophthalmol.2019Aug 18; 12 (8):1250-1261.

  6. Zhu L, Chen L, Yan L, Perkins BD, Li S, Li B*, Xu HA*, Li XJ*. Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish via Toxic Gain of Function. Front Cell Neurosci. 2019 Mar 21;13:81.

  7. Zhi-Zhi Liu, Jian Zhu, Chang-Ling Wang, Xin Wang, Ying-Ying Han, Ling-Yan Liu, Hong Xu*. CRMP2 and CRMP4 are differentially required for axon guidance and growth in zebrafish retinal neurons. Neural Plasticity 2018 Jun 21; 2018:8791304.

  8. Zhi-Zhi Liu, Zi-Long Wang, Tae-Ik Choi, Wen-Ting Huang, Han-Tsing Wang, Ying-Ying Han, Lou-Yin Zhu, Hyun-Taek Kim, Jung-Hwa Choi, Jin-Soo Lee, Hyung-Goo Kim, Jian Zhao, Yue Chen, Zhuo Lu, Xiao-Li Tian, Bing-Xing Pan, Bao-Ming Li, Cheol-Hee Kim*, Hong Xu*. Chd7 is critical for early T-cell development and thymus organogenesis in zebrafish. Am J Pathol. 2018 Apr;188(4):1043-1058.

  9. Weiwei Sheng, Ye Lu, Feng Mei, Ning Wang, Zhi-Zhi Liu, Ying-Ying Han, Han-Tsing Wang, Suqi Zou, Hong Xu*, and Xu Zhang*. Effect of Resveratrol on Sirtuins, OPA1, and Fis1 Expression in Adult Zebrafish Retina. Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4542-4551.

  10. Dell AL, Fried-Cassorla E, Xu H* and Raper JA* .cAMP-Induced Expression of Neuropilin1 Promotes Retinal Axon Crossing in the Zebrafish Optic Chiasm. J Neurosci. 2013 33(27):11076-88 (Highlighted as This Week in The Journal (TWIJ) article) (#Corresponding author)


校内链接

校外链接

Address: No. 1299 Xuefu Avenue, Honggutan District, Nanchang City, Jiangxi Province


Tel：+86-0791-83968485


E-mail：ibi@ncu.edu.cn

WeChat Official Account

Copyright ©INSTITUTE OF BIOMEDICAL INNOVATION, NANCHANG UNIVERSITY