NOW: HOME - FACULTY - Research Groups - Yu Dainan Lab
E-mail：yudainan@ncu.edu.cn
Address：Room 258, Medical Science and Technology Innovation Center
Educational Background
2019.09-2023.12, Institute of Zoology, Chinese Academy of Sciences, Ph.D.
2016.09-2019.06, Nanchang University, Master's Degree
2012.09-2016.06, Anhui University of Chinese Medicine, Bachelor's Degree
Professional Experience
2026.07-Present, Institute of Biomedical Innovation, Nanchang University / Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanchang University, Research Fellow
2024.01-2026.07, Institute of Zoology, Chinese Academy of Sciences, Postdoctoral / Special Research Assistant
Awards and Honors
2024, Third Zhou Chuan Memorial Scholarship
2024, Outstanding Communist Party Member, Institute of Zoology, Chinese Academy of Sciences
2021, Jiangxi Provincial Outstanding Master's Dissertation
2019, Jiangxi Provincial Government Graduate Scholarship
Yu Laboratory focuses on the physiological remodeling and pathological dysregulation of maternal multi-organ systems and the placenta during pregnancy. By integrating basic research with clinical application, we aim to systematically characterize the dynamic adaptive changes in maternal organs and the placenta across pregnancy, from its establishment and maintenance to postpartum recovery. We further investigate the key mechanisms underlying pregnancy-related disorders resulting from impaired maternal and/or placental adaptation, with the ultimate goal of developing new strategies for the early prediction and treatment of pregnancy-related diseases, thereby promoting maternal-fetal health.
1.Yu D*, Wan H*, Tong C*, Guang L*, Chen G*, Su J*, Zhang L, Wang Y, Xiao Z, Zhai J, Yan L, Ma W, Liang K, Liu T, Wang Y, Peng Z, Luo L, Yu R, Li W#, Qi H#, Wang H#, Shyh-Chang N#. A multi-tissue metabolome atlas of primate pregnancy[J]. Cell, 2024, 187: 764-781.e714. doi: 10.1016/j.cell.2023.11.043
2.Yu D*, Luo L*, Wang H#, Shyh-Chang N#. Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses[J]. Trends in Endocrinology & Metabolism, 2025, 36: 482-494. doi: 10.1016/j.tem.2024.07.011
3. Yu D*, Liu Q*, Qiao B*, Jiang W, Zhang L, Shen X, Xie L, Liu H, Zhang D, Yang B#, Kuang H#. Exposure to acrylamide inhibits uterine decidualization via suppression of cyclin D3/p21 and apoptosis in mice[J]. Journal of hazardous materials, 2020, 388: 121785. doi: 10.1016/j.jhazmat.2019.121785
4. Yu D, Xie X, Qiao B, Ge W, Gong L, Luo D, Zhang D, Li Y, Yang B, Kuang H. Gestational exposure to acrylamide inhibits mouse placental development in vivo[J]. Journal of hazardous materials, 2019, 367: 160-170. doi: 10.1016/j.jhazmat.2018.12.061
5. Yu D*, Jiang X*, Ge W*, Qiao B, Zhang D, Liu H, Kuang H. Gestational exposure to acrylamide suppresses luteal endocrine function through dysregulation of ovarian angiogenesis, oxidative stress and apoptosis in mice[J]. Food and chemical toxicology, 2022, 159: 112766. doi: 10.1016/j.fct.2021.112766
6. Xia S*, Yu D*, Wang Y, He B, Rong Y, Chen S, Xiao Z, Wang H, Wu H#, Yan L#. ISRIB facilitates the co-culture of human trophoblast stem cells and embryonic stem cells[J]. Cell proliferation, 2024, 57: e13599. doi: 10.1111/cpr.13599
7. Zhai J*, Guo J*, Wan H*, Qi L*, Liu L*, Xiao Z, Yan L, Schmitz DA, Xu Y, Yu D, Wu X, Zhao W, Yu K, Jiang X#, Guo F#, Wu J#, Wang H#. Primate gastrulation and early organogenesis at single-cell resolution[J]. Nature, 2022, 612: 732-738. doi: 10.1038/s41586-022-05526-y
8. Jiang X*, Zhai J*, Xiao Z*, Wu X*, Zhang D*, Wan H, Xu Y, Qi L, Wang M, Yu D, Liu Y, Wu H, Sun R, Xia S, Yu K, Guo J, Wang H. Identifying a dynamic transcriptomic landscape of the cynomolgus macaque placenta during pregnancy at single-cell resolution[J]. Developmental cell, 2023, 58: 806-821.e807. doi: 10.1016/j.devcel.2023.03.012
校内链接
校外链接
Address: No. 1299 Xuefu Avenue, Honggutan District, Nanchang City, Jiangxi Province
Tel：+86-0791-83968485
E-mail：ibi@ncu.edu.cn
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